It Doesn’t Matter How you Spell Down’s Syndrome. 17 This entry was posted in No Special Needs. and tagged art current events down syndrome Downs Syndrome Music obama photography poetry politics science style on July 20, 2013 by littlebirdsdad by I don’t care how you spell Down’s Syndrome. Spelling won’t affect my son future, open or close doors, or affect his enjoyment of life. That said, I get enough nasty emails attacking my spelling that I would like an Open Response to link back to.